Morpho-Structural Investigations of Biomaterials for Biocidal Activity

Abstract

A new wound dressing made of gelatin and Ag, was evaluated for the management of tissue reconstitution in rats. The gelatin–based dressing, with metabolic stimulation properties that favored the recovery of the skin was made of stiff sheets to supply the repairingtissue with mechanical support. The gelatin sheets enhanced the development of collagen fibers and subsequently cell proliferation at the level of stromal and vascular elements. A protocol based on the utilization of natural biomaterials in the presence of low concentrations of a biocidal was proposed which could control microbiocidal activities principally in burned and debilitated patients.