Gabapentin for the Treatment of Tremor

Author:

Faulkner Michele A1,Bertoni John M2,Lenz Thomas L3

Affiliation:

1. Michele A Faulkner PharmD, Assistant Professor of Pharmacy Practice, School of Pharmacy and Allied Health Professions, Creighton University, Omaha, NE

2. John M Bertoni MD PhD, Professor and Chairman, Department of Neurology, School of Medicine, Creighton University

3. Thomas L Lenz PharmD, Assistant Professor of Pharmacy Practice, School of Pharmacy and Allied Health Professions, Creighton University

Abstract

OBJECTIVE: To review the use of the antiepileptic drug gabapentin for the treatment of various types of tremor. DATA SOURCES: A search of biomedical literature was completed through MEDLINE and EMBASE (1993–May 2002) to identify all clinical trials pertaining to the use of gabapentin for the treatment of tremor in humans. DATA SYNTHESIS: Outcome data from the few published studies have varied widely. Patient groups have been small, and conclusions have been based largely on subjective patient and investigator ratings. CONCLUSIONS: A trial of gabapentin is warranted in patients who fail therapy with traditional agents. Improvement should be measured by a patient's perceived functional ability.

Publisher

SAGE Publications

Subject

Pharmacology (medical)

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Gabapentin Therapy of Hiccups;Annals of Pharmacotherapy;2013-05-14

2. Ataxia telangiectasia;Neurodegenerative Diseases;2005-06-02

3. Dystonia Induced by Gabapentin;Annals of Pharmacotherapy;2005-02

4. Adverse motor effects induced by antiepileptic drugs;Epileptic Disorders;2004-09

5. Tremor;Current Opinion in Neurology;2003-08

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