Progress of Circulating Tumor Cells in Cancer Management

Author:

Zhang Chufeng12,Wang Lijie12,Guan Yan2,Sun Yulan2,Liu Xiuju2,Zhu Dongyuan2,Guo Qisen2

Affiliation:

1. School of Medicine and Life Sciences, University of Jinan-Shandong, Academy of Medical Sciences, Jinan, China

2. Academy of Medical Sciences, Shandong Cancer Hospital, Jinan, Shandong, China

Abstract

Circulating tumor cells are low-frequency cells that are shed into the peripheral bloodstream from a primary solid tumor and/or metastasis. Although these cells were recognized initially in 1869, it is only in the past 2 decades that they have been isolated for use as a surrogate biomarker to monitor response to therapy, evaluate prognosis, detect tumor mutations, assist in selecting personalized medicine, and enable earlier cancer diagnosis.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology

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