Testicular Juvenile Granulosa Cell Tumor in a Newborn: Case Report and Review of the Literature-Reference-Cited by-同舟云学术

Testicular Juvenile Granulosa Cell Tumor in a Newborn: Case Report and Review of the Literature

Published:2007-07 Issue:3 Volume:15 Page:321-325
ISSN:1066-8969
Container-title:International Journal of Surgical Pathology
language:en
Short-container-title:Int J Surg Pathol

Author:

Alexiev Borislav A.¹,Alaish Samuel M.²,Sun Chen-Chih³

Affiliation:

1. University of Maryland Medical System, Department of Pathology NBW48,

2. Department of Surgery and Hospital for Children N4E37

3. Department of Pathology NBW52 (CCS), Baltimore, Maryland

Abstract

Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype 46 XY. Histopathology and immunohistochemical studies revealed the occurrence of 2 well-differentiated epithelial-like and smooth muscle-like components in the neoplasm. The morphologic clues leading to the correct diagnosis of juvenile granulosa cell tumor and the possible histogenesis are briefly discussed.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1177/1066896907302423

Reference16 articles.

1. Congenital Juvenile Granulosa Cell Tumor of the Testis in a Fetus Showing Full 69, XXY Triploidy

2. Congenital Testicular Juvenile Granulosa Cell Tumor in a Neonate with X/XY Mosaicism

3. Testicular Juvenile Granulosa Cell Tumor in an Infant with X/XY Mosaicism Clinically Diagnosed as True Hermaphroditism

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