Congenital Juvenile Granulosa Cell Tumor of the Testis in a Fetus Showing Full 69, XXY Triploidy-Reference-Cited by-同舟云学术

Congenital Juvenile Granulosa Cell Tumor of the Testis in a Fetus Showing Full 69, XXY Triploidy

Published:2005-04 Issue:2 Volume:13 Page:219-221
ISSN:1066-8969
Container-title:International Journal of Surgical Pathology
language:en
Short-container-title:Int J Surg Pathol

Author:

Kos Marina¹,Nogales Fernandez Francisco²,Kos Milan³,Stipoljev Feodora³,Kunjko Kristian¹

Affiliation:

1. Institute of Pathology, Medical School University of Zagreb, Zagreb

2. Departamento Anatomia Patologica Facultad de Medicina, Universidad de Granada, Granada, Spain

3. Sv.Duh General Hospital, Zagreb, Croatia

Abstract

Testicular juvenile granulosa cell tumor (TJGCT) occurs predominantly in infancy and may be associated with sex chromosomal abnormalities. We report a fetus aborted because of cytogenetically confirmed complete XXY triploidy. External genitalia of the fetus were female, with a short and patent vagina. The tumor presented as an abdominal multicystic mass with typical histologic and immunohistological features of JGCT. It was connected with a tubular uterus-like structure. The other gonad was an inguinally localized testis that showed histologically a Sertoli cell adenoma. Malformations typical for triploidy were also present: agenesis of the corpus callosum, stenosis of the pulmonary ostium, and hypoplasia of the lungs and adrenals. To our knowledge this is the first case of TJGCT in a triploid fetus.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1177/106689690501300216

Reference10 articles.

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5. Testicular Juvenile Granulosa Cell Tumor in an Infant with X/XY Mosaicism Clinically Diagnosed as True Hermaphroditism

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