Effects of motor cortex rTMS on lower urinary tract dysfunction in multiple sclerosis

Author:

Centonze D1,Petta F2,Versace V1,Rossi S1,Torelli F1,Prosperetti C1,Rossi St1,Marfia Ga1,Bernardi G1,Koch G1,Miano R2,Boffa L1,Finazzi-Agrò E2

Affiliation:

1. Dipartimento di Neuroscienze, Clinica Neurologica, Università Tor Vergata, Rome, Italy and Fondazione Santa Lucia IRCCS, Rome, Italy

2. Clinica Urologica, Università Tor Vergata, Rome, Italy

Abstract

We tested the effects of 5-Hz rTMS over the motor cortex in multiple sclerosis (MS) subjects complaining of lower urinary tract symptoms either in the filling or voiding phase. Our data show that motor cortex stimulation for five consecutive days over two weeks ameliorates the voiding phase of the micturition cycle, suggesting that enhancing corticospinal tract excitability might be useful to ameliorate detrusor contraction and/or urethral sphincter relaxation in MS patients with bladder dysfunction. Multiple Sclerosis 2007; 13: 269–271. http://msj.sagepub.com

Publisher

SAGE Publications

Subject

Clinical Neurology,Neurology

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