An exploratory study of diet in childhood and young adulthood and adult-onset multiple sclerosis

Author:

Black Lucinda J1,Hetherton Sarah2,Forkan Michaela2,Gonzales Edlin G3,Smith Jessica B3,Daly Alison1,Lucas Robyn M4,Langer-Gould Annette5

Affiliation:

1. School of Public Health, Curtin University, Bentley, WA, Australia

2. Department of Natural Sciences, Galway Mayo Institute of Technology, Galway, Ireland

3. Department of Research and Evaluation, Kaiser Permanente, Pasadena, CA, USA

4. National Centre for Epidemiology and Population Health, Research School of Population Health, Australian National University, Canberra, ACT, Australia/Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, WA, Australia

5. Department of Research and Evaluation, Kaiser Permanente, Pasadena, CA, USA/Neurology Department, Los Angeles Medical Center, Southern California Permanente Medical Group/Kaiser Permanente, Los Angeles, CA, USA

Abstract

There is little evidence on the role of diet in childhood/adolescence and multiple sclerosis (MS) in adulthood. The MS Sunshine Study recruited adults with recent-onset MS ( n = 602) and matched controls ( n = 653). Of these, 84% provided dietary recall for specific ages between childhood and young adulthood (6–10, 11–15 and 16–20 years). We used logistic regression to test associations between age-specific diet and case-control status. Consumption of fruit (all ages), yoghurt (all ages) and legumes (11–15 years) was associated with lower probability of adult-onset MS (all p < 0.05). These results suggest that healthy dietary habits between childhood and young adulthood may reduce MS risk.

Funder

National Institutes of Health

Multiple Sclerosis Research Australia

National Health and Medical Research Council

Multiple Sclerosis Western Australia

Curtin University of Technology

Publisher

SAGE Publications

Subject

Clinical Neurology,Neurology

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