Phytochemical Investigations of Lonchocarpus Bark Extracts from Monteverde, Costa Rica-Reference-Cited by-同舟云学术

Phytochemical Investigations of Lonchocarpus Bark Extracts from Monteverde, Costa Rica

Published:2014-04 Issue:4 Volume:9 Page:1934578X1400900
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Deskins Caitlin E.¹²,Vogler Bernhard¹,Dosoky Noura S.¹,Chhetri Bhuwan K.¹,Haber William A.³,Setzer William N.¹

Affiliation:

1. Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA

2. Department of Chemistry, Quincy University, Quincy, IL 62301, USA

3. Missouri Botanical Garden, St. Louis, MO 63166, USA

Abstract

The acetone bark extracts of three species of Lonchocarpus from Monteverde, Costa Rica, L. atropurpureus, L. oliganthus, and L. monteviridis, were screened for antibacterial, cytotoxic, and antioxidant activities. L. orotinus extract was antibacterial against Bacillus cereus (MIC = 39 μg/mL), while L. monteviridis exhibited the most antioxidant activity. None of the Lonchocarpus extracts showed cytotoxic activity against MCF-7 cells. Fatty acids and atraric acid were isolated and purified from L. atropurpureus bark, fatty acids and loliolide from L. oliganthus bark, and leonuriside A and β-D-glucopyranos-1-yl N-methylpyrrole-2-carboxylate from L. monteviridis bark. Atraric acid showed cytotoxic and antimicrobial activities.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1400900421

Reference41 articles.

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