A New Xanthone from the Pericarp of Garcinia mangostana-Reference-Cited by-同舟云学术

A New Xanthone from the Pericarp of Garcinia mangostana

Published:2013-12 Issue:12 Volume:8 Page:1934578X1300801
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Fu Manqin¹,Qiu Samuel X.²,Xu Yujuan¹,Wu Jijun¹,Chen Yulong¹,Yu Yuanshan¹,Xiao Gengsheng¹

Affiliation:

1. Guangdong Open Access Laboratory of Agri-food Processing, Sericulture and Agri-food Research Institute, Guangdong Academy of Agicultural Sciences, Guangzhou 510610, P.R. China

2. Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P.R. China

Abstract

A new prenylxanthone, garcimangostanol (1), was isolated from the EtOAc-soluble partition of the ethanol extract of the pericarp of Garcinia mangostana L., along with three known compounds, namely 8-deoxygartanin (2), 1-isomangostin (3), and garcinone C (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR and MS data. Compounds 1–4 exhibited either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNE human cancer cell lines in vitro with IC50 values from 4.0 ± 0.3 to 23.6 ± 1.5 μM by MTT colorimetric assay.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1300801219

Reference5 articles.

1. Mangostanol, a prenyl xanthone from Garcinia mangostana

2. Antioxidant Xanthones from the Pericarp of Garcinia mangostana (Mangosteen)

3. Xanthones from the bark of Garcinia merguensis

4. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

5. A Novel Depsidone and Some New Xanthones from Garcinia Species.

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