Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR-Reference-Cited by-同舟云学术

Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR

Published:2010-01-18 Issue:4 Volume:184 Page:1968-1976
ISSN:0022-1767
Container-title:The Journal of Immunology
language:en
Short-container-title:J.I.

Author:

Suzuki Takuo,Ishii-Watabe Akiko,Tada Minoru,Kobayashi Tetsu,Kanayasu-Toyoda Toshie,Kawanishi Toru,Yamaguchi Teruhide

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference42 articles.

1. Metabolic properties of IgG subclasses in man

2. An Fc receptor structurally related to MHC class I antigens

3. The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor.

4. Increasing the serum persistence of an IgG fragment by random mutagenesis

5. Analysis of the pH Dependence of the Neonatal Fc Receptor/Immunoglobulin G Interaction Using Antibody and Receptor Variants

Cited by 310 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Infliximab in Inflammatory Bowel Disease: Leveraging Physiologically Based Pharmacokinetic Modeling in the Clinical Context;Biomedicines;2024-09-01

2. Decoy peptides that inhibit TNF signaling by disrupting the TNF homotrimeric oligomer;The FEBS Journal;2024-07-14

3. Nanostructure-Mediated Transport of Therapeutics through Epithelial Barriers;International Journal of Molecular Sciences;2024-06-28

4. Translational two-pore PBPK model to characterize whole-body disposition of different-size endogenous and exogenous proteins;Journal of Pharmacokinetics and Pharmacodynamics;2024-05-01

5. An integrated methodology for quality assessment of therapeutic antibodies with potential long circulation half-life in harvested cell culture fluid using FcRn immobilized hydrophilic magnetic graphene;Talanta;2024-05