TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
Author:
Publisher
The American Association of Immunologists
Subject
Immunology,Immunology and Allergy
Reference28 articles.
1. Fcγ receptors as regulators of immune responses
2. Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond
3. Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
4. Regulation of Virus Neutralization and the Persistent Fraction by TRIM21
5. Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
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1. TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization;Frontiers in Immunology;2024-06-12
2. Impact of structural modifications of IgG antibodies on effector functions;Frontiers in Immunology;2024-01-08
3. Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach;Journal of Biological Chemistry;2023-12
4. Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates;Nature Communications;2023-04-15
5. Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models;Science;2023-03-31
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