Innovative computer-aided methods for the discovery of new kinase ligands
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, Faculty of Pharmacy, The University of Jordan, 11942, Amman, Jordan
Abstract
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc-2015-0003
Reference127 articles.
1. Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug
2. Activity-based kinase profiling of approved tyrosine kinase inhibitors
3. Trends in the exploitation of novel drug targets
4. The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication
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