Ligand-based pharmacophore modeling and machine learning for the discovery of potent aurora A kinase inhibitory leads of novel chemotypes
Author:
Funder
Deanship of Scientific Research, University of Jordan
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s11030-024-10814-y.pdf
Reference75 articles.
1. Carvajal RD, Tse A, Schwartz GK (2006) Aurora kinases: new targets for cancer therapy. Clin Cancer Res 12(23):6869–6875. https://doi.org/10.1158/1078-0432.CCR-06-1405
2. Goldenson B, Crispino JD (2015) The aurora kinases in cell cycle and leukemia. Oncogene 34(5):537–545. https://doi.org/10.1038/onc.2014.14
3. Borisa AC, Bhatt HG (2017) A comprehensive review on Aurora kinase: small molecule inhibitors and clinical trial studies. Eur J Med Chem 140:1–19. https://doi.org/10.1016/j.ejmech.2017.08.045
4. Raghu R, Devaraji V, Leena K et al (2014) Virtual screening and discovery of novel aurora kinase inhibitors. Curr Top Med Chem 14(17):2006–2019. https://doi.org/10.2174/1568026614666140929151140
5. Yan M, Wang C, He B et al (2016) Aurora-A kinase: a potent oncogene and target for cancer therapy. Med Res Rev 36(6):1036–1079. https://doi.org/10.1002/med.21399
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