Computational scaffold hopping: cornerstone for the future of drug design?
Author:
Affiliation:
1. Department of Life Science Informatics, B–IT, LIMES Program Unit Chemical Biology & Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Dahlmannstr. 2, D-53113 Bonn, Germany
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc-2017-0043
Reference16 articles.
1. Computational Exploration of Molecular Scaffolds in Medicinal Chemistry
2. The Properties of Known Drugs. 1. Molecular Frameworks
3. Analog series-based scaffolds: computational design and exploration of a new type of molecular scaffolds for medicinal chemistry
4. “Scaffold-Hopping” by Topological Pharmacophore Search: A Contribution to Virtual Screening
5. Recent Advances in Scaffold Hopping
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