Computational Exploration of Molecular Scaffolds in Medicinal Chemistry
Author:
Affiliation:
1. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Dahlmannstrasse 2, D-53113 Bonn, Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01746
Reference71 articles.
1. Lessons Learned from Molecular Scaffold Analysis
2. Rule-Based Classification of Chemical Structures by Scaffold
3. Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
4. Medicinal chemistry of target family-directed masterkeys
5. Privileged scaffolds for library design and drug discovery
Cited by 102 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Similarity searching for anticandidal agents employing a repurposing approach;Molecular Informatics;2024-01-04
2. Molecular medicinal insights into scaffold hopping-based drug discovery success;Drug Discovery Today;2024-01
3. MESPool: Molecular Edge Shrinkage Pooling for hierarchical molecular representation learning and property prediction;Briefings in Bioinformatics;2023-11-22
4. Computational Screening Using a Combination of Ligand-Based Machine Learning and Molecular Docking Methods for the Repurposing of Antivirals Targeting the SARS-CoV-2 Main Protease;DARU Journal of Pharmaceutical Sciences;2023-10-31
5. Comparative study of the mechanism of natural compounds with similar structures using docking and transcriptome data for improvingin silicoherbal medicine experimentations;Briefings in Bioinformatics;2023-09-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3