Novel isoelectric target depletion (ITaD) protocol reduces the need for specific reagents for immunogenicity testing
Author:
Affiliation:
1. Roche Pharma Research & Early Development (pRED), Pharmaceutical Sciences, Bioanalytics & Biomarker, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, Penzberg, 82377, Germany
Abstract
Publisher
Future Science Ltd
Subject
Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry
Link
https://www.future-science.com/doi/pdf/10.4155/bio-2022-0060
Reference37 articles.
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4. An Affinity Capture Elution (ACE) assay for detection of anti-drug antibody to monoclonal antibody therapeutics in the presence of high levels of drug
5. A breakthrough novel method to resolve the drug and target interference problem in immunogenicity assays
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