Bupivacaine Liposomal versus Bupivacaine: Comparative Review-Reference-Cited by-同舟云学术

Bupivacaine Liposomal versus Bupivacaine: Comparative Review

Published:2014-06 Issue:6 Volume:49 Page:539-543
ISSN:0018-5787
Container-title:Hospital Pharmacy
language:en
Short-container-title:Hosp Pharm

Author:

Noviasky John¹,Pierce Deirdre P.²,Whalen Karen³,Guharoy Roy⁴,Hildreth Kenneth⁵

Affiliation:

1. Upstate University Hospital at Community General, Syracuse, New York

2. Pharmacy Practice, St. John Fisher College, Wegmans School of Pharmacy, Rochester, New York

3. Drug Information Pharmacist, St. Joseph's Hospital Health Center, Syracuse, New York

4. University of Massachusetts Medical School, Worcester, Massachusetts

5. Upstate University Hospital at Community General, Syracuse, New York.

Abstract

Bupivacaine liposomal injection was recently approved by the US Food and Drug Administration (FDA) as a local anesthetic for use in management of postsurgical pain in adults. When compared to placebo, bupivacaine liposomal decreases postoperative pain and opioid use. This review examines the efficacy of bupivacaine liposomal when compared to conventional bupivacaine ± epinephrine using published and unpublished data provided to the FDA by the manufacturer.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Pharmacology,Pharmacy

Link

http://journals.sagepub.com/doi/pdf/10.1310/hpj4906-539

Reference12 articles.

1. Liposomal Bupivacaine: An Innovative Nonopioid Local Analgesic for the Management of Postsurgical Pain

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3. Bupivacaine Extended-Release Liposome Injection for Prolonged Postsurgical Analgesia in Patients Undergoing Hemorrhoidectomy: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

4. A phase 3, randomized, placebo-controlled trial of DepoFoam® bupivacaine (extended-release bupivacaine local analgesic) in bunionectomy

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