A Connectome of the Male Drosophila Ventral Nerve Cord-Reference-Cited by-同舟云学术

A Connectome of the Male Drosophila Ventral Nerve Cord

Published:2024-05-23 Issue: Volume: Page:
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Author:

Takemura Shin-ya¹,Hayworth Kenneth J¹^ORCID,Huang Gary B¹^ORCID,Januszewski Michal²^ORCID,Lu Zhiyuan¹^ORCID,Marin Elizabeth C³^ORCID,Preibisch Stephan¹^ORCID,Xu C Shan¹^ORCID,Bogovic John¹^ORCID,Champion Andrew S³⁴^ORCID,Cheong Han SJ¹^ORCID,Costa Marta³^ORCID,Eichler Katharina³^ORCID,Katz William¹^ORCID,Knecht Christopher¹^ORCID,Li Feng¹^ORCID,Morris Billy J³^ORCID,Ordish Christopher¹^ORCID,Rivlin Patricia K¹^ORCID,Schlegel Philipp³⁴^ORCID,Shinomiya Kazunori¹,Stürner Tomke⁴³^ORCID,Zhao Ting¹^ORCID,Badalamente Griffin³^ORCID,Bailey Dennis¹^ORCID,Brooks Paul³^ORCID,Canino Brandon S¹^ORCID,Clements Jody¹^ORCID,Cook Michael¹^ORCID,Duclos Octave¹^ORCID,Dunne Christopher R³^ORCID,Fairbanks Kelli¹^ORCID,Fang Siqi³,Finley-May Samantha¹^ORCID,Francis Audrey¹^ORCID,George Reed¹,Gkantia Marina³^ORCID,Harrington Kyle¹^ORCID,Hopkins Gary Patrick¹^ORCID,Hsu Joseph³^ORCID,Hubbard Philip M¹^ORCID,Javier Alexandre³^ORCID,Kainmueller Dagmar¹^ORCID,Korff Wyatt¹^ORCID,Kovalyak Julie¹^ORCID,Krzemiński Dominik³^ORCID,Lauchie Shirley A¹^ORCID,Lohff Alanna¹^ORCID,Maldonado Charli¹^ORCID,Manley Emily A¹^ORCID,Mooney Caroline¹^ORCID,Neace Erika¹^ORCID,Nichols Matthew¹,Ogundeyi Omotara¹^ORCID,Okeoma Nneoma¹^ORCID,Paterson Tyler¹^ORCID,Phillips Elliott¹^ORCID,Phillips Emily M¹,Ribeiro Caitlin¹^ORCID,Ryan Sean M¹^ORCID,Rymer Jon Thomson¹^ORCID,Scott Anne K¹,Scott Ashley L¹^ORCID,Shepherd David⁵^ORCID,Shinomiya Aya¹^ORCID,Smith Claire¹,Smith Natalie¹^ORCID,Suleiman Alia¹^ORCID,Takemura Satoko¹^ORCID,Talebi Iris¹^ORCID,Tamimi Imaan FM³^ORCID,Trautman Eric T¹^ORCID,Umayam Lowell¹^ORCID,Walsh John J¹^ORCID,Yang Tansy¹^ORCID,Rubin Gerald M¹^ORCID,Scheffer Louis K¹^ORCID,Funke Jan¹^ORCID,Saalfeld Stephan¹^ORCID,Hess Harald F¹^ORCID,Plaza Stephen M¹^ORCID,Card Gwyneth M¹^ORCID,Jefferis Gregory SXE⁴³^ORCID,Berg Stuart¹^ORCID

Affiliation:

1. Janelia Research Campus, Howard Hughes Medical Institute

2. Google Research, Google LLC

3. Department of Zoology, University of Cambridge

4. MRC Laboratory of Molecular Biology

5. School of Biological Sciences, University of Southampton

Abstract

Animal behavior is principally expressed through neural control of muscles. Therefore understanding how the brain controls behavior requires mapping neuronal circuits all the way to motor neurons. We have previously established technology to collect large-volume electron microscopy data sets of neural tissue and fully reconstruct the morphology of the neurons and their chemical synaptic connections throughout the volume. Using these tools we generated a dense wiring diagram, or connectome, for a large portion of the Drosophila central brain. However, in most animals, including the fly, the majority of motor neurons are located outside the brain in a neural center closer to the body, i.e. the mammalian spinal cord or insect ventral nerve cord (VNC). In this paper, we extend our effort to map full neural circuits for behavior by generating a connectome of the VNC of a male fly.

Publisher

eLife Sciences Publications, Ltd

Link

https://elifesciences.org/reviewed-preprints/97769v1/pdf

Reference25 articles.

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