The lasting influence of LSD1 in the blood-Reference-Cited by-同舟云学术

The lasting influence of LSD1 in the blood

Published:2013-06-18 Issue: Volume:2 Page:
ISSN:2050-084X
Container-title:eLife
language:en
Short-container-title:

Author:

Dent Sharon YR¹,Chandra Joya²

Affiliation:

1. Department of Molecular Carcinogenesis, MD Anderson Cancer Center, Texas, United States

2. Department of Pediatrics Research and the Department of Molecular Carcinogenesis, MD Anderson Cancer Center, Texas, United States

Abstract

An enzyme called LSD1 that controls the development of blood cells by manipulating gene expression in progenitor cells could be a therapeutic target for leukemia.

Publisher

eLife Sciences Publications, Ltd

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://cdn.elifesciences.org/articles/00963/elife-00963-v1.pdf

Reference12 articles.

1. LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells;Adamo;Nat Cell Biol,2011

2. The histone LSD1 demethylase in stemness and cancer transcription programs;Amente;Biochim Biophys Acta,2013

3. Chromatin modifications as therapeutic targets in MLL-rearranged leukemia;Deshpande;Trends Immunol,2012

4. Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability;Foster;Mol Cell Biol,2010

5. The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells;Harris;Cancer Cell,2012

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery and synthesis of novel indole derivatives-containing 3-methylenedihydrofuran-2(3H)-one as irreversible LSD1 inhibitors;European Journal of Medicinal Chemistry;2019-08

2. Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation;Trends in Molecular Medicine;2019-06

3. Pharmacological Inhibition of LSD1 for Cancer Treatment;Molecules;2018-12-04

4. Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives;Journal of Hematology & Oncology;2016-06-17

5. Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia;Journal of Hematology & Oncology;2016-03-12