Antiulcer and Ulcer Healing Potential of Some Medicinal Plants: A Review

Abstract

Ulcers are open sores on the skin or mucus membrane characterized by a superficial loss of tissue. Ulcers are mainly occurs due to the disturbance of the normal equilibrium caused by either enhanced aggression or diminished mucosal resistance to possible ulcerative agents. Main adverse effects were reported for synthetic medicines available in market, involve the gastrointestinal tract discomfort. Plant based traditional medicines are commonly used all over the world since years as they found safe and effective. Many Medicinal plants and their parts (root, rhizome, bark, leaves and fruits) are currently being used for ulcer treatment. The aim of this review was to report the parts of the plants used for Extract preparation, active constituents present in them and Antiulcer models used for the evaluation. Many Medicinal plants have the potential for the prevention and treatment of ulcers. Detailed investigation, chemical studies, isolation and further studies need to be conducted to identify the active components and elucidate the exact mechanisms of action.