Allicin Gel: A cure to Dermatological ailments: Formulation and Characterization

Abstract

Skin is the outer masking of the human body. Thus human skin comes in more contact with microbial infections and other ailments for curing such microbial ailments a source of efficacious antimicrobial products had to be used. The herbal source of medicines are primary choice to humans as for their being repeatedly powerful and much less side-impact inflicting. The source of the product being herbal is expected to be both efficacious and having no negative outcomes. One of the most effective and useful herbal ingredients for treatment of multifaceted diseases in humans is Garlic (Allium sativum L. fam. Alliaceae). The purpose of using Allicin extracted from Garlic is to treat dermatological ailments in humans. Allicin (diallylthiosulfinate) is an element of garlic and has a broad range of biological activities. Allicin when used, proliferation of both fungi and bacteria can be inhibited when administered within a pharmacological range and it also shows efficacy against antibiotic resistant strains such as methicillin resistant Staphylococcus aureus (MRSA). Allicin induces cell death and inhibits cell proliferation in mammalian cancer cells. The gel base is prepared via the use of Carbopol934 and Triethanolamine. Extracted allicin is blended to it and allicin gel is prepared for its antimicrobial dermatological application.