Hypouricemic Significance of Ledum Palustre (Marsh Tea): A Review

Author:

Singh Bhuwanendra1,Gupta Jitendra2,Mohan Rohit3,Gupta Reena2,Pal Kanchan4

Affiliation:

1. Department of Pharmacognosy, NKBR College of Pharmacy and Research Centre, Meerut, Uttar Pradesh, India- 245206.

2. Institute of Pharmaceutical Research, GLA University, Mathura-281406, Uttar Pradesh, India-281406.

3. Department of Pharmacology, Goel Institute of Pharmacy and Sciences, Lucknow, U.P, India-226028.

4. Department of Biochemistry, Jhunjhun Wala, P.C College, Ayodhya, Faizabad- India-224001.

Abstract

The current review article is based on the facts to reveal the biological potentials of the genus ledum, and specie palustre. Although in the article all the species are well described with their distribution in all over the world and their pharmacological activities are also discussed. Rhododendron tomantosum is also known as Marsh Tea or northern Labrador tea, which is an evergreen shrub having the height of about 40 cm and the plant has about ten species in all over the world. Article has very informative aspect regarding Hypouricemic Significance of Ledum palustre (L. palustre), its chemical compounds extracted and analyzed by different spectroscopic and chromatographic techniques to report the active principles from the oil of the Rhododendron tomantosum fresh leaves. The main active compounds were found are given as (41.0–43.4%) ledol (23.3–26.7%) and ascaridole (15.1–4.5%). L. palustre has a very significant role in the gout and arthritis occurs due the presence of high amount of uric acid in the blood plasma. Various dosage forms are mentioned in the review article to explore the potentials of the drug. Hence according to literature if L. palustre is significantly capable to reduce the high level of the uric acid if give in the potency if 30 c (diluted 30 times)) and 1 M ((1000 dilutions) to the patients, and may be a good alternative to the allopurinol. So, this drug is frequently used in the homeopathic system of medicine to get the hypouricemic significance in the human beings.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference27 articles.

1. Munjal Y. API Textbook of Medicine. The Association of Physicians. 9th ed: New Delhi India. 2012.

2. Shaffique S, Ahmed S, Rehman T, Mumtaz W, Anwar H, and Husain G. Anti-hyperuricemic potential of Rhododendron tomentosum Harmaja syn Ledum palustre L 30c and 1M in potassium oxonate induced rat model. Indian Journal of Traditional Knowledge. 2018; 17 (1): 724-731.

3. URL: https://en.wikipedia.org/wiki/Labrador_tea (Accessed on April 28, 2020)

4. Ren G, Chang W, Miao T, Wang C. Investigation and Utilization of Ledum palustre L Resources in the North Temperate Zone. IOP Conf. Series: Earth and Environmental Science 371. 2019; 032053.

5. Zhang L, Wang, Xu M, Hu1 X. Chemical Composition and Antibacterial Activity of the essential Oil from Chinese Wild Ledum palustre L on Vibrio Parahaemolyticus, International Journal of Food and Nutritional Science. 2017; 4 (1): 8- 12.

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