Antihyperglycemic activity of Ficus carica leaves extracts on Streptozotocin induced diabetic rats-Reference-Cited by-同舟云学术

Antihyperglycemic activity of Ficus carica leaves extracts on Streptozotocin induced diabetic rats

Published:2021-08-06 Issue: Volume: Page:4151-4156
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Roy Tathagata¹,Paul Susanta¹,Roy Chowdhury Victor¹,Das Arijit²,Chandra Srikanta³,Das Avik⁴,Jana Abhishek⁵,Bhattacharya Muniraj⁵,Ghosh Nibir⁵

Affiliation:

1. Assistant Professor, Department of Pharmaceutical Technology, JIS University, Kolkata -700109.

2. Assistant Professor, Bharat Technology, Uluberia, Howrah.

3. Assistant Professor, Jakir Hossain Institute of Pharmacy, Murshidabad.

4. Assistant Professor, Gupta College of Technological Sciences, Asansol.

5. Department of Pharmaceutical Technology, JIS University, Kolkata 700109.

Abstract

Antihyperglycemic activity of leave extracts of Ficus carica was evaluated on STZ induced diabetic rats. Diabetes was induced in albino Wistar rats of either sex by intraperitoneal (60mg/kg b.w.) of STZ, freshly dissolved in citrate buffer (0.01 M, pH 4.5). Ficus carica leave extract in different solution (viz. petroleum ether, ethyloacetate, methanol and aqueous) were administered to diabetic rats for 9 days. The effect of extracts on blood glucose and body weight was studies on day 1st and 9th. The study showed that the ethyl acetate, methanolic and aqueous extract of Ficus sarmentosa leaves reduced blood glucose level and body weight significantly. This may justify the use of ficus species as ethanomedical medicine for treatment of diabetes mellitus.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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