The Lactobacillus brevis Prebiotic Pure Exo polysaccharide and its Nano crystalline Characterization, anti-colon cancer and cytotoxicity-Reference-Cited by-同舟云学术

The Lactobacillus brevis Prebiotic Pure Exo polysaccharide and its Nano crystalline Characterization, anti-colon cancer and cytotoxicity

Published:2021-11-30 Issue: Volume: Page:5998-6002
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

El-Waseif Amr A.¹,Abobaker Rabea A.²,Abdel-Monem M. O.²,A. A. Attia²,Hassan Mervat G.²

Affiliation:

1. Botany and Microbiology Dept., Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt.

2. Botany and Microbiology Dept., Faculty of Science, Banha University, Egypt.

Abstract

The present work established that the exopolysaccharide taken from Lactobacillus brevis and its Nano crystalline form are very efficient as an anti-colon cancer. The produced exopolysaccharide and its Nano crystalline were preliminarily conformed by UV spectroscopy, FTIR spectroscopy and TEM. The UV analysis revealed the peak at 258 nm which corresponds to exopolysaccharide and shifted to 270 for Nano crystalline. The uniform spherical shape and size was detected by TEM. The exopolysaccharide and nano prebiotic exopolysaccharide were evaluated for its cytotoxicity on CACO2 and WI-38 was tested by MTT assay. The result indicated decrease in cell viability. The present study highlighted the possibility of utilizing exopolysaccharide and its Nano crystalline form from Lactobacillus brevis for human applications as it enhanced anti-colon cancer.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference29 articles.

1. Xiaohua WU. and Z. Lina. E versus Z geometry in β-d-arabino-hexopyranosidulose oximes. Carbohydrate Research. 2009; 344: 2209–2216.

2. Doleyres Y., Schaub L. and Lacroix C. Comparison of the functionality of exopolysaccharides produced in situ or added as bioingredients on yogurt properties. Journal of Dairy Science. 2005; 88: 4146–4156.

3. Van Calsteren M. R., Pau-Roblot C., Bégin A. and Roy D. Structure determination of the exopolysaccharide produced by Lactobacillus rhamnosus strains RW-9595M and R. Biochemical Journal. 2002; 363: 7–17.

4. Wollowski I., Rechkemmer G. and L. Pool-Zobel B. Protective role of probiotics and prebiotics in colon cancer. Am. J. Clin. Nutr. 2001; 73: 451–455.

5. Rafter J. Probiotics and colon cancer. Best Pract Res Clin Gastroenterol. 2003; 5: 849-859.

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