CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration-Reference-Cited by-同舟云学术

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CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration

Published:2019-12-17 Issue:2 Volume:130 Page:673-685
ISSN:0021-9738
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:

Author:

Nobles Christopher L.,Sherrill-Mix Scott^ORCID,Everett John K.,Reddy Shantan,Fraietta Joseph A.,Porter David L.,Frey Noelle,Gill Saar I.,Grupp Stephan A.,Maude Shannon L.,Siegel Donald L.,Levine Bruce L.,June Carl H.^ORCID,Lacey Simon F.^ORCID,Melenhorst J. Joseph,Bushman Frederic D.

Funder

National Institutes of Health

Gabrielle’s Angel Foundation

PennCHOP Microbiome Program

Novartis Institute for Biomedical Research

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Link

https://www.jci.org/articles/view/130144/files/pdf

Reference72 articles.

1. Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

2. Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

3. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

4. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

5. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

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