Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia-Reference-Cited by-同舟云学术

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

Published:2015-09-02 Issue:303 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Porter David L.¹,Hwang Wei-Ting²,Frey Noelle V.¹,Lacey Simon F.³,Shaw Pamela A.²,Loren Alison W.¹,Bagg Adam³,Marcucci Katherine T.³,Shen Angela⁴,Gonzalez Vanessa³,Ambrose David³,Grupp Stephan A.⁵,Chew Anne³,Zheng Zhaohui³,Milone Michael C.³,Levine Bruce L.³,Melenhorst Jan J.³,June Carl H.³

Affiliation:

1. Division of Hematology/Oncology, Department of Medicine, and Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

2. Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

3. Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

4. Novartis Pharmaceutical Corporation, One Health Plaza, East Hanover, NJ 07936, USA.

5. Division of Oncology, Department of Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.

Abstract

CAR T cells persist and sustain remissions in advanced chronic lymphocytic leukemia.

Funder

NIH

Pennsylvania Department of Health

Leukemia and Lymphoma Society

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference32 articles.

1. Managing high-risk CLL during transition to a new treatment era: stem cell transplantation or novel agents?

2. The Treatment of Relapsed Refractory Chronic Lymphocytic Leukemia

3. A Phase I Study on Adoptive Immunotherapy Using Gene-Modified T Cells for Ovarian Cancer

4. Adoptive Transfer of Chimeric Antigen Receptor Re-directed Cytolytic T Lymphocyte Clones in Patients with Neuroblastoma

5. Treatment of Metastatic Renal Cell Carcinoma With Autologous T-Lymphocytes Genetically Retargeted Against Carbonic Anhydrase IX: First Clinical Experience

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