Intratumoral androgen biosynthesis associated with 3β-hydroxysteroid dehydrogenase 1 promotes resistance to radiotherapy in prostate cancer
Author:
Funder
U.S. Department of Defense
American Cancer Society
National Cancer Institute
VeloSano Foundation
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://www.jci.org/articles/view/165718/files/pdf
Reference48 articles.
1. Neoadjuvant and Adjuvant Hormonal and Chemotherapy for Prostate Cancer
2. Phase III Trial of Long-Term Adjuvant Androgen Deprivation After Neoadjuvant Hormonal Cytoreduction and Radiotherapy in Locally Advanced Carcinoma of the Prostate: The Radiation Therapy Oncology Group Protocol 92–02
3. Optimizing androgen deprivation therapy with radiation therapy for aggressive localized and locally advanced prostate cancer
4. Effect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer
5. Dose Escalated Radiotherapy Alone or in Combination With Short-Term Androgen Suppression for Intermediate Risk Prostate Cancer: Outcomes From the NRG Oncology/RTOG 0815 Randomized Trial
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1. Importance of 3β-hydroxysteroid dehydrogenases and their clinical use in prostate cancer;Endocrine-Related Cancer;2024-04-29
2. Adrenal-Permissive HSD3B1 Genotype—An Invisible Stimulator of Prostate Cancer Mortality;JAMA Network Open;2024-03-20
3. Review of Current Treatment Intensification Strategies for Prostate Cancer Patients;Cancers;2023-11-28
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