Adrenal-Permissive HSD3B1 Genotype—An Invisible Stimulator of Prostate Cancer Mortality
Author:
Affiliation:
1. Desai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, Florida
2. Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida
Publisher
American Medical Association (AMA)
Link
https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2816501/schiffer_2024_ic_240030_1710263196.30875.pdf
Reference7 articles.
1. Targeting the androgen signaling axis in prostate cancer.;Dai;J Clin Oncol,2023
2. A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer.;Chang;Cell,2013
3. Germline hsd3b1 genetics and prostate cancer outcomes.;Thomas;Urology,2020
4. Adrenal-permissive germline HSD3B1 allele and prostate cancer outcomes.;McKay;JAMA Netw Open,2024
5. Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.;Castro;J Clin Oncol,2013
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