CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation
Author:
Funder
NIH
Incyte
AACR
Cancer Research Institute
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/138729/files/pdf
Reference53 articles.
1. Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
2. Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways
3. T cell metabolic fitness in antitumor immunity
4. Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
5. The CD28 Signaling Pathway Regulates Glucose Metabolism
Cited by 63 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice;Nature Communications;2024-09-11
2. Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis;Cell Reports;2024-09
3. Phase I studies of davoceticept (ALPN-202), a PD-L1-dependent CD28 co-stimulator and dual PD-L1/CTLA-4 inhibitor, as monotherapy and in combination with pembrolizumab in advanced solid tumors (NEON-1 and NEON-2);Journal for ImmunoTherapy of Cancer;2024-08
4. CD28 co-stimulation: novel insights and applications in cancer immunotherapy;Nature Reviews Immunology;2024-07-25
5. Immunometabolism of CD8+ T cell differentiation in cancer;Trends in Cancer;2024-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3