Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice-Reference-Cited by-同舟云学术

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Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice

Published:2024-09-11 Issue:1 Volume:15 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Jiang Xiaoxue,liu Kan^ORCID,Luo Peixiang,Li Zi,Xiao Fei,Jiang Haizhou,Wu Shangming,Tang Min,Yuan Feixiang,Li Xiaoying,Shu Yousheng^ORCID,Peng Bo,Chen Shanghai,Ni Shihong,Guo Feifan^ORCID

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41467-024-52059-1.pdf

Reference56 articles.

1. Kuk, J. L., Saunders, T. J., Davidson, L. E. & Ross, R. Age-related changes in total and regional fat distribution. Ageing Res. Rev. 8, 339–348 (2009).

2. Santos, A. L. & Sinha, S. Obesity and aging: molecular mechanisms and therapeutic approaches. Ageing Res. Rev. 67, 101268 (2021).

3. Kim, J. G. & Horvath, T. L. mTOR signaling fades POMC neurons during aging. Neuron 75, 356–357 (2012).

4. Camell, C. D. et al. Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. Nature 550, 119–123 (2017).

5. Gao, H. et al. Age-induced reduction in human lipolysis: a potential role for adipocyte noradrenaline degradation. Cell Metab. 32, 1–3 (2020).

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