Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice
Author:
Funder
National Institute of Diabetes and Digestive and Kidney Diseases
National Pancreas Foundation
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/129717/files/pdf
Reference25 articles.
1. The Epidemiology of Pancreatitis and Pancreatic Cancer
2. Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway
3. Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme Y
4. Increased Activation of Hereditary Pancreatitis-associated Human Cationic Trypsinogen Mutants in Presence of Chymotrypsin C
5. Chymotrypsin C (Caldecrin) Stimulates Autoactivation of Human Cationic Trypsinogen
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