Slowing ribosome velocity restores folding and function of mutant CFTR-Reference-Cited by-同舟云学术

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Slowing ribosome velocity restores folding and function of mutant CFTR

Published:2019-10-28 Issue:12 Volume:129 Page:5236-5253
ISSN:0021-9738
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:

Author:

Oliver Kathryn E.^ORCID,Rauscher Robert,Mijnders Marjolein^ORCID,Wang Wei,Wolpert Matthew J.,Maya Jessica^ORCID,Sabusap Carleen M.,Kesterson Robert A.,Kirk Kevin L.,Rab Andras,Braakman Ineke^ORCID,Hong Jeong S.^ORCID,Hartman John L.,Ignatova Zoya^ORCID,Sorscher Eric J.

Funder

Cystic Fibrosis Foundation

National Institutes of Health

Burroughs Wellcome Fund

Deutsche Forschungsgemeinschaft FOR1805

German Cystic Fibrosis Foundation muko e.V.

Netherlands Science Organization

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Link

https://www.jci.org/articles/view/124282/files/pdf

Reference63 articles.

1. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

2. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

3. Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

4. Structures of the human and Drosophila 80S ribosome

5. Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1α

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1. Mutation accumulation in H. sapiens F508del CFTR countermands dN/dS type genomic analysis;PLOS ONE;2024-07-18

2. The Folding Pathway of ABC Transporter CFTR: Effective and Robust;Journal of Molecular Biology;2024-07

3. COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation;Scientific Reports;2024-05-03

4. PTI-801 (posenacaftor) shares a common mechanism with VX-445 (elexacaftor) to rescue p.Phe508del-CFTR;European Journal of Pharmacology;2024-03

5. Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes;Nucleic Acids Research;2024-02-07

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