A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice-Reference-Cited by-同舟云学术

A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice

Published:2024-01-04 Issue:4 Volume:134 Page:
ISSN:1558-8238
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:

Author:

Metzger Peter J.,Zhang Aileen,Carlson Bradley A.,Sun Hui,Cui Zhenzhong^ORCID,Li Yongqi,Jahnke Marshal T.,Layton Daniel R.,Gupta Meenakshi B.,Liu Naili,Kostenis Evi,Gavrilova Oksana,Chen Min,Weinstein Lee S.

Funder

National Institute for Diabetes, Digestive and Kidney Diseases

Deutsche Forschungsgemeinschaft

Publisher

American Society for Clinical Investigation

Link

https://www.jci.org/articles/view/165418/files/pdf

Reference61 articles.

1. Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

2. Functional Characterization and Structural Modeling of Obesity Associated Mutations in the Melanocortin 4 Receptor

3. Modulation of Blood Pressure by Central Melanocortinergic Pathways

4. Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

5. A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors

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