An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice-Reference-Cited by-同舟云学术

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

Published:2012-02-01 Issue:2 Volume:122 Page:553-557
ISSN:0021-9738
Container-title:Journal of Clinical Investigation
language:en
Short-container-title:J. Clin. Invest.

Author:

Kinross Kathryn M.,Montgomery Karen G.,Kleinschmidt Margarete,Waring Paul,Ivetac Ivan,Tikoo Anjali,Saad Mirette,Hare Lauren,Roh Vincent,Mantamadiotis Theo,Sheppard Karen E.,Ryland Georgina L.,Campbell Ian G.,Gorringe Kylie L.,Christensen James G.,Cullinane Carleen,Hicks Rodney J.,Pearson Richard B.,Johnstone Ricky W.,McArthur Grant A.,Phillips Wayne A.

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Reference29 articles.

1. Mutation of the PIK3CA Gene in Ovarian and Breast Cancer

2. High Frequency of Mutations of the PIK3CA Gene in Human Cancers

3. Class I PI3K in oncogenic cellular transformation

4. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

5. The biology of ovarian cancer: new opportunities for translation

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