Dose Selection for Carcinogenicity Studies of Pharmaceuticals: Systemic Exposure to Phenacetin at Carcinogenic Dosage in the Rat
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference9 articles.
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2. A systemic exposure-based alternative to the maximum tolerated dose for carcinogenicity studies of human therapeutics;Contrera;J. Am. Coll. Toxicol.,1995
3. Proceedings of the Second International Conference on Harmonisation,1994
4. Carcinogenicity of analgesics: Long-term treatment of Sprague–Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen);Johansson;Int. J. Cancer.,1981
5. Determination of phemacetin and its major metabolites in human plasma and urine by high-performance liquid chromatography;Mineshita;J. Chromatogr.,1986
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