Site-directed mutagenesis of the regulatory domain of escherichia coli carbamoyl phosphate synthetase identifies crucial residues for allosteric regulation and for transduction of the regulatory signals 1 1Edited by A. R. Fersht-Reference-Cited by-同舟云学术

Site-directed mutagenesis of the regulatory domain of escherichia coli carbamoyl phosphate synthetase identifies crucial residues for allosteric regulation and for transduction of the regulatory signals 1 1Edited by A. R. Fersht

Published:2000-06 Issue:4 Volume:299 Page:979-991
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Fresquet Vicente,Mora Paz,Rochera Lourdes,Ramón-Maiques Santiago,Rubio Vicente,Cervera Javier

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference44 articles.

1. Binding of N-acetyl-L-glutamate to rat liver carbamoyl phosphate synthetase (ammonia);Alonso;Eur. J. Biochem.,1983

2. Affinity cleavage of carbamoyl-phosphate synthetase I localizes regions of the enzyme interacting with the molecule of ATP that phosphorylates carbamate;Alonso;Eur. J. Biochem.,1995

3. Oxidative inactivation of carbamoyl phosphate synthetase (ammonia). Mechanism and sites of oxidation, degradation of the oxidized enzyme, and inactivation by glycerol, EDTA, and thiol protecting agents;Alonso;J. Biol. Chem.,1992

4. Binding of allosteric affectors to carbamyl-phosphate synthetase from Escherichia coli;Anderson;Biochemistry,1977

5. Current Protocols in Molecular Biology;Ausubel,1997

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