The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA-Reference-Cited by-同舟云学术

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

Published:2001-06 Issue:5 Volume:309 Page:1189-1199
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Fatemi Mehrnaz,Hermann Andrea,Pradhan Shriharsa,Jeltsch Albert

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference52 articles.

1. Cancer epigenetics comes of age;Jones;Nature Genet.,1999

2. DNA methylation in health and disease;Robertson;Nature Rev. Genet.,2000

3. Methylation moves into medicine;Hendrich;Curr. Biol.,2000

4. DNA modification by methyltransferases;Cheng;Curr. Opin. Struct. Biol.,1995

5. Structure and function of DNA methyltransferases;Cheng;Annu. Rev. Biophys. Biomol. Struct.,1995

Cited by 212 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Role of DNMT Methyltransferases and TET Dioxygenases in the Maintenance of the DNA Methylation Level;Biomolecules;2024-09-04

2. Non-nucleoside inhibitors of DNMT1 and DNMT3 for targeted cancer therapy;Pharmacological Research;2024-09

3. A Tunable, Ultrasensitive Threshold in Enzymatic Activity Governs the DNA Methylation Landscape;2024-06-29

4. DNA Methyltransferase 3A: A Significant Target for the Discovery of Inhibitors as Potent Anticancer Drugs;Mini-Reviews in Medicinal Chemistry;2024-03

5. Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization;Journal of Cell Biology;2024-02-20