Characterization of Cytochrome P450 2A4 and 2A5-Catalyzed 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Metabolism
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Biochemistry,Biophysics
Reference24 articles.
1. Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific N-Nitrosamines
2. Kinetic Analysis of the Activation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Heterologously Expressed Human P450 Enzymes and the Effect of P450- Specific Chemical Inhibitors on This Activation in Human Liver Microsomes
3. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate
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