Studies on Menadione as an Inhibitor of the cdc25 Phosphatase
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference11 articles.
1. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.
2. Effects of sodium ascorbate (vitamin C) and 2-methyl-1,4-naphthoquinone (vitamin K3) treatment on human tumor cell growth in vitro. I. Synergism of combined vitamin C and K3 action
3. Menadione: Spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines
4. DNA strand scission and free radical production in menadione-treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase.
5. Vitamin K3 Inhibits Growth of Human Hepatoma HepG2 Cells by Decreasing Activities of Both p34cdc2 Kinase and Phosphatase
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1. Menadione reduces CDC25B expression and promotes tumor shrinkage in gastric cancer;Therapeutic Advances in Gastroenterology;2020-01
2. Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells;Scientific Reports;2018-11-16
3. Use of molecular dynamics simulations to estimate the solubility of menadione in supercritical CO2 using Chrastil's model;Fluid Phase Equilibria;2017-02
4. Covalent inhibition of protein tyrosine phosphatases;Molecular BioSystems;2017
5. Solubility of menadione and dichlone in supercritical carbon dioxide;Fluid Phase Equilibria;2016-09
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