Clinical features and diagnosis of Ph - negative myeloproliferative neoplasms occurring in conjunction with the antiphospholipid syndrome-Reference-Cited by-同舟云学术

Clinical features and diagnosis of Ph - negative myeloproliferative neoplasms occurring in conjunction with the antiphospholipid syndrome

Published:2019-07-15 Issue:7 Volume:91 Page:93-99
ISSN:2309-5342
Container-title:Terapevticheskii arkhiv
language:
Short-container-title:Terapevticheskii arkhiv

Author:

Melikyan A L,Subortseva I N,Koloshejnova E A,Gilyazitdinova E A,Shashkina K S,Gorgidze L A,Tratsevskaya Zh V,Margolin O V

Abstract

Thrombosis is a serious and extremely dangerous disease that has a negative impact on the quality and longevity. Antiphospholipid syndrome (APS) is a pathology characterized by recurring venous, arterial, microvasculature thrombosis, pregnancy pathology with loss of the fetus and the synthesis of antiphospholipid antibodies. A high risk of thrombotic complications is also observed in patients with myeloproliferative neoplasms (MPN). This article presents a description of three clinical cases of Ph - negative myeloproliferative diseases, occurring in conjunction with APS. In all cases, recurrent thrombosis allowed to suspect the presence of two diseases - MPN and APS.

Publisher

Consilium Medicum

Subject

General Medicine,Endocrinology, Diabetes and Metabolism,History,Family Practice

Link

https://ter-arkhiv.ru/0040-3660/article/viewFile/33631/pdf

Reference29 articles.

1. Меликян А.Л., Туркина А.Г., Абдулкадыров К.М., Зарицкий А.Ю., Афанасьев Б.В., Шуваев В.А., Ломаиа Е.Г., Морозова Е.В., Байков В.В., Голенков А.К., Суборцева И.Н., Соколова М.А., Ковригина А.М., Мартынкевич И.С., Грицаев С.В., Судариков А.Б., Суханова Г.А., Иванова В.Л., Капланов К.Д., Константинова Т.С., Поспелова Т.И., Агеева Т.А., Шатохин Ю.В., Савченко В.Г. Клинические рекомендации по диагностике и терапии Ph - негативных миелопролиферативных заболеваний (истинная полицитемия, эссенциальная тромбоцитемия, первичный миелофиброз). Гематология и трансфузиология. 2014;59(4):31-56.

2. Меликян А.Л., Туркина А.Г., Ковригина А.М., Суборцева И.Н., Судариков А.Б., Соколова М.А., Зарицкий А.Ю., Ломаиа Е.Г., Шуваев В.А., Грицаев С.В., Мартынкевич И.С., Афанасьев Б.В., Морозова Е.В., Байков В.В., Голенков А.К., Иванова В.Л., Капланов К.Д., Поспелова Т.И., Агеева Т.А., Шатохин Ю.В., Савченко В.Г. Клинические рекомендации по диагностике и терапии Ph - негативных миелопролиферативных заболеваний (истинная полицитемия, эссенциальная тромбоцитемия, первичный миелофиброз) (редакция 2016 г.). Гематология и трансфузиология. 2017;62(1):25-60.

3. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

4. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

5. A retrospective study on 226 polycythemia vera patients: impact of median hematocrit value on clinical outcomes and survival improvement with anti-thrombotic prophylaxis and non-alkylating drugs