Safety Evaluation of Rare Sugar Syrup: Single-dose Oral Toxicity in Rats, Reverse Mutation Assay, Chromosome Aberration Assay, and Acute Non-Effect Level for Diarrhea of a Single Dose in Humans-Reference-Cited by-同舟云学术

Safety Evaluation of Rare Sugar Syrup: Single-dose Oral Toxicity in Rats, Reverse Mutation Assay, Chromosome Aberration Assay, and Acute Non-Effect Level for Diarrhea of a Single Dose in Humans

Published:2015 Issue:5 Volume:56 Page:211-216
ISSN:0015-6426
Container-title:Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
language:en
Short-container-title:Journal of the Food Hygienics Society of Japan

Author:

YAMADA Takako¹,IIDA Tetsuo¹,TAKAMINE Satoshi¹,HAYASHI Noriko¹,OKUMA Kazuhiro¹

Affiliation:

1. Matsutani Chemical Industry Co., Ltd., Research & Development

Publisher

Japanese Society for Food Hygiene and Safety

Subject

General Medicine

Link

https://www.jstage.jst.go.jp/article/shokueishi/56/5/56_211/_pdf

Reference13 articles.

1. 1) Iida, T., Yamada, T., Hayashi, N., Okuma, K., Izumori, K., Ishii, R., Matsuo, T. Reduction of abdominal fat accumulation in rats by 8-week ingestion of a newly developed sweetener made from high fructose corn syrup. Food Chemistry, 138, 781–785 (2013).

2. 2) Hayashi, N., Yamada,T., Takamine, S., Iida, T., Okuma, K., Tokuda, M. Weight reducing effect and safety evaluation of rare sugar syrup by a randomized double-blind, parallel-group study in human. J. Funct. Foods, 11, 152–159 (2014).

3. 3) Takamine, S., Nakamura, M., Iida, T., Okuma, K., Izumori, K. Manufacturing method of rare sugar syrup through alkali isomerization and its inhibitory effect of alpha-glucosidase. Ouyou Toushitsu Kagaku (Bull. Appl. Glycosci.), 5, 44–49 (2015).

4. 4) Matsuo, T., Ishii, R., Iida, T., Yamada, T., Takamine, S., Shirai, Y. Ninety-day oral toxicity study of rare sugar syrup in male Wistar rats. Current Topics in Toxicology, 7, 41–49 (2011).

5. 5) Maron, D. M., Ames, B. N. Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173–215 (1983).

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