Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α
-
Published:2023
Issue:2
Volume:48
Page:211-221
-
ISSN:0386-7196
-
Container-title:Cell Structure and Function
-
language:en
-
Short-container-title:Cell Struct. Funct.
Author:
Sogawa Ashuei1, Komori Ryota2, Yanagitani Kota2, Ohfurudono Miku1, Tsuru Akio1, Kadoi Koji1, Kimata Yukio1, Yoshida Hiderou3, Kohno Kenji2
Affiliation:
1. Laboratory of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Institute of Science and Technology (NAIST) 2. Institute for Research Initiatives, Nara Institute of Science and Technology (NAIST) 3. Department of Biochemistry and Molecular Biology, Graduate School of Science, University of Hyogo
Publisher
Japan Society for Cell Biology
Subject
Cell Biology,Molecular Biology,Physiology,General Medicine
Reference29 articles.
1. Adamson, B., Norman, T.M., Jost, M., Cho, M.Y., Nuñez, J.K., Chen, Y., Villalta, J.E., Gilbert, L.A., Horlbeck, M.A., Hein, M.Y., Pak, R.A., Gray, A.N., Gross, C.A., Dixit, A., Parnas, O., Regev, A., and Weissman, J.S. 2016. A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response. Cell, 167: 1867–1882. 2. Ali, M.M.U., Bagratuni, T., Davenport, E.L., Nowak, P.R., Silva-Santisteban, M.C., Hardcastle, A., McAndrews, C., Rowlands, M., Morgan, G.J., Aherne, W., Collins, I., Davies, F.E., and Pearl, L.H. 2011. Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response. EMBO J., 30: 894–905. 3. Arakawa, S., Yunoki, K., Izawa, T., Tamura, Y., Nishikawa, S., and Endo, T. 2016. Quality control of nonstop membrane proteins at the ER membrane and in the cytosol. Sci. Rep., 6: 30795. 4. Concha, N.O., Smallwood, A., Bonnette, W., Totoritis, R., Zhang, G., Federowicz, K., Yang, J., Qi, H., Chen, S., Campobasso, N., Choudhry, A.E., Shuster, L.E., Evans, K.A., Ralph, J., Sweitzer, S., Heerding, D.A., Buser, C.A., Su, D.S., and DeYoung, M.P. 2015. Long-range inhibitor-induced conformational regulation of human IRE1 alpha endoribonuclease activity. Mol. Pharmacol., 88: 1011–1023. 5. Doma, M.K. and Parker, R. 2006. Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature, 440: 561–564.
|
|