Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity-Reference-Cited by-同舟云学术

Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity

Published:2015-10-05 Issue:6 Volume:88 Page:1011-1023
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Concha Nestor O.,Smallwood Angela,Bonnette William,Totoritis Rachel,Zhang Guofeng,Federowicz Kelly,Yang Jingsong,Qi Hongwei,Chen Stephanie,Campobasso Nino,Choudhry Anthony E.,Shuster Leanna E.,Evans Karen A.,Ralph Jeff,Sweitzer Sharon,Heerding Dirk A.,Buser Carolyn A.,Su Dai-Shi,DeYoung M. Phillip

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference46 articles.

1. Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

2. Joint X-ray and neutron refinement withphenix.refine

3. XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

4. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

5. The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma Pathogenesis

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