Biliverdin Reductase-A Deficiency Brighten and Sensitize Biliverdin-binding Chromoproteins

Author:

Kobachi Kenju1,Kuno Sota2,Sato Shinya1,Sumiyama Kenta3,Matsuda Michiyuki14,Terai Kenta1

Affiliation:

1. Laboratory of Bioimaging and Cell Signaling, Research Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University

2. Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University

3. Laboratory for Mouse Genetic Engineering, RIKEN Center for Biosystems Dynamics Research

4. Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University

Publisher

Japan Society for Cell Biology

Subject

Cell Biology,Molecular Biology,Physiology,General Medicine

Reference46 articles.

1. Akagi, T., Sasai, K., and Hanafusa, H. 2003. Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation. Proc. Natl.Acad. Sci. USA, 100: 13567–13572.

2. Auldridge, M.E., Satyshur, K.A., Anstrom, D.M., and Forest, K.T. 2012. Structure-guided engineering enhances a phytochrome-based infrared fluorescent protein. J. Biol. Chem., 287: 7000–7009.

3. Bisht, K., Canesin, G., Cheytan, T., Li, M., Nemeth, Z., Csizmadia, E., Woodruff, T.M., Stec, D.E., Bulmer, A.C., Otterbein, L.E., and Wegiel, B. 2019. Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. J. Immunol., 202: 2982–2990.

4. Chen, W., Maghzal, G.J., Ayer, A., Suarna, C., Dunn, L.L., and Stocker, R. 2018. Absence of the biliverdin reductase-a gene is associated with increased endogenous oxidative stress. Free Radic. Biol. Med., 115: 156–165.

5. Chernov, K.G., Redchuk, T.A., Omelina, E.S., and Verkhusha, V.V. 2017. Near-Infrared Fluorescent Proteins, Biosensors, and Optogenetic Tools Engineered from Phytochromes. Chem. Rev., 117: 6423–6446.

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