Author:
Nassiri Setare,Aminimoghaddam Soheila,Sadaghian Marjan Ranjbar,Nikandish Mahboobeh,Jamshidnezhad Niousha,Saffarieh Elham
Abstract
This study was conducted to evaluate the diagnostic accuracy of the cervical biopsy under colposcopic vision. This retrospective study was performed on 190 women, who were selected from a total of 412 cases referring for colposcopy in one year. All patients underwent colposcopy and loop electrosurgical excision procedure (LEEP). After the investigation of demographic characteristics and data confirmation, colposcopic characteristics were examined. Then, the diagnostic indicators and diagnostic accuracy of the cervical biopsy under colposcopic vision were determined. The mean age of patients was 35.51± 5.91 years. In smokers, the percentage of cancer and CIN3 cases was higher than in normal individuals, and this difference was statistically significant in terms of the frequency of cancerous lesions (P = 0.2). A comparison of colposcopic biopsy with LEEP has shown that the frequency of advanced cases in LEEP has been detected more, and the correlation coefficient (kappa) indicated the weak agreement between the findings of colposcopically directed biopsy (CDB) and LEEP methods. (k = 0.23). The diagnostic accuracy of the cervical biopsy under colposcopic vision for cervical cancer is effectively high. It is recommended that this procedure be performed to diagnose cancerous lesions; however, contrary to what is seen in colposcopy, malignant cases may be spreading and follow-up of patients can affect therapeutic performance.
Subject
Cell Biology,Neurology (clinical),Molecular Biology,Orthopedics and Sports Medicine
Reference29 articles.
1. Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020 Feb;8(2):e191-e203. Epub 2019 Dec 4. Erratum in: Lancet Glob Health. 2022 Jan;10(1):e41.
2. Khodakarami N, Hosseini S, Yavari P, Farzaneh F, Etemad K, Salehpour S. Human Papillomavirus Infection Prevalence in Women Referred to Health Clinic of Shahid Beheshti University of Medical Sciences, Tehran, Iran. irje. 2012; 7 (4) :35-42. URL: http://irje.tums.ac.ir/article-1-29-en.html
3. Ndifon CO, Al-Eyd G. Atypical Squamous Cells of Undetermined Significance. 2020 Dec 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; Last Update: April 28, 2022. https://www.ncbi.nlm.nih.gov/books/NBK557739/
4. Massad LS, Einstein MH, Huh WK, Katki HA, Kinney WK, Schiffman M, Solomon D, Wentzensen N, Lawson HW; 2012 ASCCP Consensus Guidelines Conference. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. J Low Genit Tract Dis. 2013 Apr;17(5 Suppl 1):S1-S27. Erratum in: J Low Genit Tract Dis. 2013 Jul;17(3):367.
5. Mello V, Sundstrom RK. Cervical Intraepithelial Neoplasia. 2020 Aug 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan. PMID: 31335091.
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