NIH Toolbox Cognition Battery Feasibility in Individuals With Williams Syndrome
Author:
Condy Emma E.1, Becker Lindsey2, Farmer Cristan3, Kaat Aaron J.4, Chlebowski Colby5, Kozel Beth A.6, Thurm Audrey7
Affiliation:
1. Emma E. Condy, National Institute of Mental Health 2. Lindsey Becker, Eunice Kennedy Shriver National Institute of Child Health & Human Development 3. Cristan Farmer, National Institute of Mental Health 4. Aaron J. Kaat, Northwestern University Feinberg School of Medicine 5. Colby Chlebowski, National Institute of Mental Health 6. Beth A. Kozel, National Heart, Lung, and Blood Institute 7. Audrey Thurm, National Institute of Mental Health
Abstract
Abstract
The NIH Toolbox Cognition Battery (NIHTB-CB) was developed for epidemiological and longitudinal studies across a wide age span. Such a tool may be useful for intervention trials in conditions characterized by intellectual disability (ID), such as Williams syndrome (WS). Three NIHTB-CB tasks, including two executive functioning (Flanker, Dimensional Change Card Sort) and one episodic memory (Picture Sequence Memory) task, were given to 47 individuals with WS, ages 4 to 50, to evaluate feasibility (i.e., proportion of valid administrations) in this population. Findings indicated that NIHTB-CB tests showed good feasibility. Flanker and DCCS age-corrected scores were negatively correlated with age and showed floor effects, indicating these scores may not be useful for quantifying performance on these NIHTB-CB tests in ID.
Publisher
American Association on Intellectual and Developmental Disabilities (AAIDD)
Subject
Psychiatry and Mental health,Neurology (clinical),Arts and Humanities (miscellaneous),Developmental and Educational Psychology,Neuropsychology and Physiological Psychology,General Medicine,Pediatrics, Perinatology and Child Health
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