Self-Assembly of Gold Nanoparticles on Gold Core-Induced Polypyrrole Nanohybrids for Electrochemical Sensor of Dopamine

Abstract

Gold core-induced polypyrrole nanohybrids (Au–PPyNHs) were successfully synthesized via in situ chemical oxidation polymerization of pyrrole molecules, and their structure was directly confirmed and characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction. Furthermore, gold nanoparticles (AuNPs) were assembled onto the as-prepared Au–PPyNHs by electrostatic interaction to fabricate the nanohybrids of Au–PPyNH–Au. The created Au–PPyNH–Au nanohybrids was immobilized onto glassy carbon electrode and applied to construct dopamine (DA) sensor. We found that the fabricated sensor with Au–PPyNH–Au nanohybrids is highly specific probe for sensing DA. The Au–PPyNH–Au based DA sensor has a linear detection range from 1[Formula: see text][Formula: see text]M to 0.321 mM and a detection limit of 0.32[Formula: see text][Formula: see text]M.