INFLUENCE OF LIMITED-PROJECTION ON FLUORESCENCE MOLECULAR TOMOGRAPHY-Reference-Cited by-同舟云学术

INFLUENCE OF LIMITED-PROJECTION ON FLUORESCENCE MOLECULAR TOMOGRAPHY

Published:2012-07 Issue:03 Volume:05 Page:1250020
ISSN:1793-5458
Container-title:Journal of Innovative Optical Health Sciences
language:en
Short-container-title:J. Innov. Opt. Health Sci.

Author:

HE YUN¹,CAO XU¹,LIU FEI¹,LUO JIANWEN¹²,BAI JING¹

Affiliation:

1. Department of Biomedical Engineering, Tsinghua University, Beijing 100084, P. R. China

2. Center for Biomedical Imaging Research, Tsinghua University, Beijing 100084, P. R. China

Abstract

Challenges remain in imaging fast biological processes in vivo with fluorescence molecular tomography (FMT) due to the long data acquisition time. Data acquisition with limited projections can greatly reduce the time consumption, but the influence of limited-projection on reconstruction quality is currently unclear. Both numerical simulations and a phantom experiment are conducted to analyze this problem. Through a systematic investigation of all the results reconstructed from different numbers of projections, we evaluate the influence of limited-projection data on FMT. A mouse experiment is also performed to validate our work. A general relationship between the number of projections and reconstruction quality is obtained which indicates that the projection number of three is preferred for fast FMT experiment.

Publisher

World Scientific Pub Co Pte Lt

Subject

Biomedical Engineering,Atomic and Molecular Physics, and Optics,Medicine (miscellaneous),Electronic, Optical and Magnetic Materials

Link

https://www.worldscientific.com/doi/pdf/10.1142/S1793545812500204

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