Data filtering method for correlated X-ray scattering (CXS)-Reference-Cited by-同舟云学术

Data filtering method for correlated X-ray scattering (CXS)

Published:2019-12-03 Issue:02 Volume:34 Page:2050018
ISSN:0217-9849
Container-title:Modern Physics Letters B
language:en
Short-container-title:Mod. Phys. Lett. B

Author:

Liu Shengjun¹,Schenk Gundolf²³

Affiliation:

1. Department of Electronic and Information Engineering, Xiamen City University, 1263 Qianpu Road, Siming District, Xiamen 361008, China

2. Department of Applied Physics, Stanford University, Stanford, CA 94305, USA

3. SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA

Abstract

Correlated X-ray scattering (CXS) which was explored to study the conformations of biological macromolecules in solution was studied further in this paper. In our experiment, three kinds of solution sample such as the Peg solution, the linear DNA from salmon sperm and the plasmid DNA were scattered by X-ray Free Electron Laser in Spring8 in Japan. And the X-ray scattering patterns with low rate of signal and noise were obtained. In order to improve the correlated signal, a cluster data filtering method for billions of scattering patterns was put forward. Finally, some of the scattering patterns with high artifacts which were related with potential sources of experimental set-up had been characterized and removed. In addition, different clusters were clarified so as to compute and analyze the angular autocorrelation of different clusters more effectively.

Funder

National Institutes of Health

Stanford NIH Biotechnology Training

US Department of Energy Office of Science

National Nature Science Foundation of China

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,Statistical and Nonlinear Physics

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0217984920500189

Reference18 articles.

1. An assessment of the resolution limitation due to radiation-damage in X-ray diffraction microscopy

2. Single-particle structure determination by correlations of snapshot X-ray diffraction patterns

3. Structure determination through correlated fluctuations in x-ray scattering

4. Observation of correlated X-ray scattering at atomic resolution

5. High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography