Affiliation:
1. School of Aerospace Engineering, Tsinghua University, Beijing 100084, P. R. China
Abstract
Facing the gradually increased prevalence of heart failure (HF) and the shortage of donated hearts, the blood pump is widely used to prolong the life of end-stage HF patients: however, the pump generates continuous flow under constant rotational speed, declining the arterial pulsatility and causing related complications. Previous studies show that synchronous copulsation might be the best control strategy for restoring pulsatility, but synchronous strategies are needed to monitor the phase of the heartbeat, which will make the controller complex and impair its robustness. Here, we compare constant speed, synchronous copulsation in a model of a cardiovascular system with a blood pump, which shows that copulsation offers more arterial pulsatility, less pump power-consumption, and thus better battery endurance, and constant speed offers a greater ventricular unloading effect. Meanwhile, we design a strategy based on transforming left ventricular pressure, which is easier to implement and has similar effect to synchronous copulsation.
Funder
National Key R&D Program of China
Publisher
World Scientific Pub Co Pte Lt
Cited by
5 articles.
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